abstract：:Curcumin, an aromatic phytoextract from the turmeric (Curcuma longa) rhizome, has been used for centuries for a variety of purposes, not the least of which is medicinal. A growing body of evidence suggests that curcumin has a broad range of potentially therapeutic pharmacological properties, including anti-inflammator...

journal_title：Annals of hepatology

authors： Hu RW,Carey EJ,Lindor KD,Tabibian JH

更新日期：2017-11-01 00:00:00

abstract：INTRODUCTION:The availability of curative hepatitis C therapies has created an opportunity to improve delivery and access. Local providers, government, industry, and community groups in Prince Edward Island developed an innovative province-wide care model. Our goal was to describe the first year of program implementati...

journal_title：Annals of hepatology

authors： Francheville JW,Rankin R,Beck J,Hoare C,Materniak S,German G,Barrett L,Bunimov-Wall N,Smyth D

更新日期：2017-09-01 00:00:00

abstract：:In the not so distant past, organs from hepatitis C infected donors were either discarded or rarely transplanted into HCV viremic recipients - but never allocated to non-infected patients. However, the simplicity, ease and unprecedented success rates of HCV direct acting antiviral regimens has raised the possibility o...

journal_title：Annals of hepatology

authors： Hussaini T,Yoshida EM

更新日期：2017-09-01 00:00:00

abstract：:Alcoholic liver disease (ALD) is a definition encompassing a spectrum of disorders ranging from simple steatosis to cirrhosis and hepatocellular carcinoma. Excessive alcohol consumption triggers a series of metabolic reactions that affect the liver by inducing lipogenesis, increasing oxidative stress, and causing abno...

journal_title：Annals of hepatology

authors： Boccuto L,Abenavoli L

更新日期：2017-07-01 00:00:00

abstract：:Neuroendocrine tumors comprise approximately 1-2% of all gastrointestinal tumors, and while the liver is the most common site for metastasis of these tumors, primary hepatic neuroendocrine tumors are very rare entities. Since first being reported in 1958, there have been less than 150 cases reported in the literature....

journal_title：Annals of hepatology

authors： DeLuzio MR,Barbieri AL,Israel G,Emre S

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND AND AIM:Intrahepatic cholestasis of pregnancy (ICP) is linked with increased risk of fetal complications. An accurate diagnostic test is needed to diagnose this disorder on time. We aimed to assess sensitivity and specificity of laboratory tests used for diagnosis of intrahepatic cholestasis of pregnancy and...

journal_title：Annals of hepatology

authors： Jurate K,Rimantas Z,Jolanta S,Vladas G,Limas K

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND AND AIMS:The presence of dermatologic reaction as an adverse event to sorafenib treatment in patients with unresectable hepatocellular carcinoma has been indicated as a prognostic factor for survival in a recent prospective analysis. To date, this is the only clinical predictor of treatment response, which c...

journal_title：Annals of hepatology

authors： Branco F,Alencar RS,Volt F,Sartori G,Dode A,Kikuchi L,Tani CM,Chagas AL,Pfiffer T,Hoff P,Carrilho FJ,Mattos AA

更新日期：2017-03-01 00:00:00

abstract：:Hepatitis B virus infection seems to protect against steatosis and insulin resistance decreasing NAFLD. Metabolic syndrome has been associated with increased risk of disease progression to cirrhosis and liver cancer in hepatitis B. HBsAg seroclearance increased over time and it could be a confounding factor when analy...

journal_title：Annals of hepatology

authors： Morales MR,Sendra C,Romero-Gomez M

更新日期：2017-03-01 00:00:00

abstract：INTRODUCTION AND AIM:Liver transplantation (LT) provides durable survival for hepatocellular carcinoma (HCC). However, there is continuing debate concerning the impact of wait time and acceptable tumor burden on outcomes after LT. We sought to review outcomes of LT for HCC at a single, large U.S. center, examining the ...

journal_title：Annals of hepatology

authors： Palmer WC,Lee D,Burns J,Croome K,Rosser B,Patel T,Keaveny AP,Pungpapong S,Satyanarayana R,Yataco M,Nakhleh R,Musto KR,Canabal AM,Turnage AK,Hodge DO,Nguyen JH,Harnois DM

更新日期：2017-01-01 00:00:00

abstract：:The increase of incidences of Hepatocellular Carcinoma (HCC) will continue in the next decades. The therapies about hepatitis C infection has been questioned as a risk factor. Some authors emphasized that sustained virologic response (SVR) with interferon-based therapy reduced the risk of developing HCC. In contrast, ...

journal_title：Annals of hepatology

authors： Chinchilla-López P,Qi X,Yoshida EM,Méndez-Sánchez N

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Minimal hepatic encephalopathy (MHE) can reverse after short-term treatment. However, relapse rate of MHE after stopping treatment has not been studied so far. We aimed to evaluate long-term (9 months) efficacy of a short-term (3 months) treatment of MHE with lactulose/rifaximin, for maintenance of remissi...

journal_title：Annals of hepatology

authors： Goyal O,Sidhu SS,Kishore H

更新日期：2017-01-01 00:00:00

abstract：: Background and aims. Steroid-related hepatotoxicity has become one of the most relevant causes of drug induced liver cholestasis. Some patients do not improve after standard medical treatment (SMT) and may therefore require other approaches, like extracorporeal liver support. MATERIAL AND METHODS:We report four case...

journal_title：Annals of hepatology

authors： Díaz FC,Sáez-González E,Benlloch S,Álvarez-Sotomayor D,Conde I,Polo B,García M,Rodríguez M,Prieto M

更新日期：2016-11-01 00:00:00

abstract：: Introduction and aim. Many transplant programs have expanded eligibility to include patients previously ineligible because of advanced age. Outcomes of simultaneous liver-kidney transplantation (SLK) in recipients with advanced age are not known. MATERIAL AND METHODS:Data from patients undergoing transplantation bet...

journal_title：Annals of hepatology

authors： Croome KP,Lee DD,Burns JM,Perry DK,Nguyen JH,Keaveny AP,Wadei HM,Taner CB

更新日期：2016-11-01 00:00:00

abstract：: Progressive familial intrahepatic cholestasis (PFIC) is a heterogeneous group of autosomal recessive cholestatic diseases of childhood and represents the main indication for liver transplantation at this age; PFIC2 involves ABCB11 gene, that encodes the ATPdependent canalicular bile salt export pump (BSEP). Benign in...

journal_title：Annals of hepatology

authors： Vitale G,Pirillo M,Mantovani V,Marasco E,Aquilano A,Gamal N,Francalanci P,Conti F,Andreone P

更新日期：2016-09-01 00:00:00

abstract：UNLABELLED: Introduction and aim. Given that early identification of non-alcoholic fatty liver disease (NAFLD) is an important issue for primary prevention of hepatic disease, the objectives of this study were to evaluate the efficacy of the product of triglyceride and glucose levels (TyG) for screening simple steatosi...

journal_title：Annals of hepatology

authors： Simental-Mendía LE,Simental-Mendía E,Rodríguez-Hernández H,Rodríguez-Morán M,Guerrero-Romero F

更新日期：2016-09-01 00:00:00

abstract：: Hepatic involvement in AL amyloidosis may present as acute liver failure. Historically, liver transplantation in these cases has achieved poor outcomes due to progress of amyloidosis and non-hepatic organ damage. In the era of bortezomib treatment, the prognosis of AL amyloidosis has been markedly improved and may al...

journal_title：Annals of hepatology

authors： Elnegouly M,Specht K,Zoller H,Matevossian E,Bassermann F,Umgelter A

更新日期：2016-07-01 00:00:00

abstract：UNLABELLED: Background and rationale. The REPLACE study (NCT01571583) investigated telaprevir-based triple therapy in patients who have recurrent genotype 1 hepatitis C virus (HCV) infection following liver transplantation and are on a stable immunosuppressant regimen of tacrolimus or cyclosporin A. Patients received t...

journal_title：Annals of hepatology

authors： Forns X,Didier S,Mutimer D,Fagiuoli S,Navasa M,Agarwal K,Berenguer M,Colombo M,Herzer K,Nevens F,Daems B,Janssen K,Ouwerkerk-Mahadevan S,Kimko H,Lathouwers E,Witek J,Van Solingen-Ristea R

更新日期：2016-07-01 00:00:00

abstract：:Ursodeoxycholic acid (UDCA) is the first choice medication for most cholestatic hepatopathies, due to its capability to counteract inflammation and bile-acid-induced liver damage, two common features in cholestasis. However, UDCA is usually contraindicated in obstructive cholestasis, due to the alleged risk of biliary...

journal_title：Annals of hepatology

authors： Bessone F,Roma MG

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND AND AIMS:We conducted an individual participant data (IPD) pooled analysis on the diagnostic accuracy of magnetic resonance elastography (MRE) to detect fibrosis stage in liver transplant recipients. MATERIAL AND METHODS:Through a systematic literature search, we identified studies on diagnostic performance...

journal_title：Annals of hepatology

authors： Singh S,Venkatesh SK,Keaveny A,Adam S,Miller FH,Asbach P,Godfrey EM,Silva AC,Wang Z,Murad MH,Asrani SK,Lomas DJ,Ehman RL

更新日期：2016-05-01 00:00:00

abstract：UNLABELLED: Background and rationale for the study. There is currently no definition of post-transjugular intrahepatic portosystemic shunt (TIPS) liver failure (PTLF), which constitutes a barrier to standardization of TIPS results reporting and limits the ability to compare liver failure incidence across clinical studi...

journal_title：Annals of hepatology

authors： Gaba RC,Lakhoo J

更新日期：2016-03-01 00:00:00

abstract：:In our current era where shortage of liver grafts is commonplace, utilization of traumatic liver grafts may represent an opportunity to expand the organ donor pool without compromising graft survival. However, data on liver transplantation using a fractured liver allograft is scarce, with only small case series and re...

journal_title：Annals of hepatology

authors： Fong ZV,Patel MS,Yeh H,Markmann JF,Vagefi PA

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND STUDY AIMS:Chronic liver disease (CLD) can cause hepatopulmonary syndrome (HPS), defined as triad of liver disease, hypoxemia, and intrapulmonary vascular dilation (IPVD). The aim of this study was to determine the evidence of IPVD in a cohort of pediatric patients with CLD pre- and post-liver transplant...

journal_title：Annals of hepatology

authors： Khositseth A,Treepongkaruna S,Khemakanok K,Teeraratkul S,Pansrimangkorn V,Thirapattaraphan C,Leelaudomlipi S

更新日期：2016-01-01 00:00:00

abstract：:The objective of this study was to establish modified cutoff values of serum alpha-fetoprotein (AFP) according to hepatitis status. While AFP is used as a serum marker in the diagnosis or monitoring of hepatocellular carcinoma (HCC), its use as a screening method to the general population is controversial. We evaluate...

journal_title：Annals of hepatology

authors： Chun S,Rhie SY,Ki CS,Kim JE,Park HD

更新日期：2015-11-01 00:00:00

abstract：:About 80% of patients with liver cirrhosis may have glucose metabolism disorders, 30% show overt diabetes mellitus (DM). Prospective studies have demonstrated that DM is associated with an increased risk of hepatic complications and death in patients with liver cirrhosis. DM might contribute to liver damage by promoti...

journal_title：Annals of hepatology

authors： García-Compeán D,González-González JA,Lavalle-González FJ,González-Moreno EI,Maldonado-Garza HJ,Villarreal-Pérez JZ

更新日期：2015-11-01 00:00:00

abstract：UNLABELLED:Background and rationale for the study. FGF19/15 is a gut-derived hormone presumably governing bile acid (BA) synthesis and gallbladder (GB) refilling. FGF19 mRNA is present in human GB cholangiocytes (hGBECs); however, the physiological significance of GB-derived FGF19 remains unknown. We investigated wheth...

journal_title：Annals of hepatology

authors： Barrera F,Azócar L,Molina H,Schalper KA,Ocares M,Liberona J,Villarroel L,Pimentel F,Pérez-Ayuso RM,Nervi F,Groen AK,Miquel JF

更新日期：2015-09-01 00:00:00

abstract：:Despite reports that mortality is increasing, overall case fatality due to hepatitis C virus (HCV) is thought to be low. Given the variability in published rates, we aimed to synthesize estimates of liver-specific case fatality and all-cause mortality in chronic HCV according to follow-up duration, sustained viral res...

journal_title：Annals of hepatology

authors： Szabo SM,Samp JC,Walker DR,Lane S,Cline SK,Gooch KL,Jimenez-Mendez R,Levy AR

更新日期：2015-09-01 00:00:00

abstract：INTRODUCTION:Liver metastases (LM) are crucial prognostic manifestation of gastrointestinal stromal tumors (GIST). With the advent of tyrosine kinase inhibitors (TKI), management of metastatic GIST has radically changed. Long clinical follow-up provides an increased proportion of GIST patients with LM who are candidate...

journal_title：Annals of hepatology

authors： Vassos N,Agaimy A,Hohenberger W,Croner RS

更新日期：2015-07-01 00:00:00

abstract：:MicroRNAs represent a class of non-coding RNA molecules that negatively regulate gene expression either by repressing translation or by inducing degradation of messenger RNA. Studies have shown that, as regulators of gene expression, microRNAs are widely involved in various human diseases, including hepatitis B virus-...

journal_title：Annals of hepatology

authors： Yu K,Shi G,Li N

更新日期：2015-07-01 00:00:00

abstract：UNLABELLED:BACKGROUND AND RATIONALE FOR THE STUDY: Genome-wide association studies have identified host genetic variation to be critical for spontaneous clearance and treatment response in patients infected with hepatitis C virus. Recently, the role of the IFNL3 polymorphisms in influencing the spontaneous clearance of...

journal_title：Annals of hepatology

authors： Origa R,Marceddu G,Danjou F,Perseu L,Satta S,Demartis FR,Piga A,Longo F,Lai ME,Vacquer S,Galanello R

更新日期：2015-05-01 00:00:00

abstract：INTRODUCTION:Fatigue is an important clinical finding in the hepatitis virus chronic infection. However, the absence of scales to measure fatigue, translated and validated for Brazilian Portuguese, prevents access to information essential in clarifying specific clinical conditions in this population. AIM:The aim of th...

journal_title：Annals of hepatology

authors： Miranda-Pettersen K,Morais-de-Jesus M,Daltro-Oliveira R,Dantas Duarte Dias A,Teles C,Schinoni MI,Miranda-Scippa Â,Paraná R,Quarantini LC

更新日期：2015-05-01 00:00:00

abstract：:Organs from deceased donors with traumatic abdominal injury, peritoneal contamination and open abdomen are usually discarded due to risks of transmission of severe infections to the recipient. There are no specific recommendations regarding organ utilization from these donors, but they might be an unexplored source ab...

journal_title：Annals of hepatology

authors： Grezzana Filho TJ,Chedid AD,Leipnitz I,Chedid MF,Kruel CD,Kruel CR

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Transarterial chemoembolisation (TACE), having demonstrated survival benefits, is the treatmentof choice in intermediate-stage hepatocellular carcinoma, although there is great heterogeneity in its clinical application. MATERIAL AND METHODS:A survey was sent to the Madrid Regional hospitals to assess applic...

journal_title：Annals of hepatology

authors： Peña AM,Núñez-Martínez Ó,Díaz-Sánchez A,Pons-Renedo F,Gómez-Rubio M,Polo-Lorduy B,Lledó-Navarro JL,Trapero-Marugán M,Ladero-Quesada JM,Poves-Martínez E,Ibáñez-Pinto A,Martín-Algívez AM,Lozano-Maya M,González-Alonso R,Piqueras

更新日期：2015-03-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is a relevant issue in public health owing to its epidemiological burden. It represents the most common chronic liver disease in the general population and is expected to increase in future as a result of an ageing population. The only currently recommended treatment for NAFLD...

journal_title：Annals of hepatology

authors： Abenavoli L,Peta V,Milic N

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:We compared mortality and complications of chronic hepatitis C between treated and untreated Mexican patients after long-term follow-up. We used a time-to-event analysis and identified the prognostic factors. MATERIAL AND METHODS:Seventy-four patients with chronic hepatitis C were studied. They were ≥ 18 ye...

journal_title：Annals of hepatology

authors： Martínez-Macías RF,Cordero-Pérez P,Juárez-Rodríguez OA,Chen-López CY,Martínez-Carrillo FM,Alarcón-Galván G,Mercado-Hernández R,Muñoz-Espinosa LE

更新日期：2015-01-01 00:00:00

abstract：:A 59-year-old man with T-cell prolymphocytic leukemia on alemtuzumab presented with neutropenic fever, intermittent nausea, and multiple ill-defined low attenuation foci in the liver on abdominal computed tomography scan which were suspicious for metastatic disease. Histological examination revealed the diagnosis of a...

journal_title：Annals of hepatology

authors： Putra J,Suriawinata AA

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Approximately 180 million persons (~2.8%) globally are estimated to be infected by hepatitis C virus (HCV). HCV prevalence in Mexico has been estimated to be between 1.2 and 1.4%. The aim of present work was to determine the prevalence of HCV infection in patients and family members attending two primary car...

journal_title：Annals of hepatology

authors： López-Colombo A,Meléndez-Mena D,Sedeño-Monge V,Camacho-Hernández JR,Vázquez-Cruz E,Morales-Hernández ER,Sosa-Jurado F,Márquez-Domínguez L,Santos-López G

更新日期：2014-11-01 00:00:00

abstract：:Mirizzi's syndrome (MS) is a rare complication of the inveterate biliary lithiasis. Diagnostic and therapeutic standardization is still missing, especially since laparoscopic cholecystectomy has become the gold standard approach for symptomatic cholelithiasis. Our study is a retrospective analysis based on a case-seri...

journal_title：Annals of hepatology

authors： Piccinni G,Sciusco A,De Luca GM,Gurrado A,Pasculli A,Testini M

更新日期：2014-09-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is considered to be a manifestation of liver metabolic damage and is related to insulin resistance and genetic susceptibility. Inflammation mediated by Kupffer cells (KCs) is of critical importance to the development of NAFLD. The primary role of KCs in NAFLD is considered to ...

journal_title：Annals of hepatology

authors： Wenfeng Z,Yakun W,Di M,Jianping G,Chuanxin W,Chun H

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND AND AIM:The effect of preoperative transcatheter arterial chemoembolization (TACE) on the short- and long-term outcome of resectable hepatocellular carcinoma (HCC) is controversial. We conducted a retrospective evaluation of this aspect using data from our center. MATERIAL AND METHODS:A total of 656 consecu...

journal_title：Annals of hepatology

authors： Jianyong L,Jinjing Z,Wentao W,Lunan Y,Qiao Z,Bo L,Tianfu W,Minqing X,Jiaying Y,Yongang W

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:In non-alcoholic fatty liver disease (NALFD), it has often been assumed that an elevation in serum ferritin is likely related to inflammation rather than iron overload. MATERIAL AND METHODS:Patients referred with NAFLD were entered into a clinical study of phlebotomy therapy. A liver biopsy with liver iron ...

journal_title：Annals of hepatology

authors： Beaton MD,Chakrabarti S,Adams PC

更新日期：2014-05-01 00:00:00